Join Us in the Fight Against Disease

Cancer cells have the ability to reprogram metabolic pathways to provide themselves with the raw materials they need to grow and thrive. It has long been known that they hijack glutamine pathways to use the nitrogen and carbon for both survival and proliferation. Cancer cells are "addicted" to glutamine. For energy, cancer cells absorb ten times or more of the glucose of normal healthy cells. They are hungry. Our strategy is to research both glutamine blockers and glucose blockers to deprive cancer cells of these nutrients. A weakened tumour will be unable to develop resistance to chemotherapeutics and radiation, and our own innate immune systems will be given a fighting chance. Targeted substrates can undo what the tumour cells have done in terms of re-programming both cellular metabolism and mitochondrial function.

Powerful new strategies in the field of metabolomics will aid us in precision analysis of metabolites and therefore advance the knowledge of the metabolic pathways cancer is using to cause this dysregulation.

Many chronic and degenerative diseases have similar dysregulated metabolic pathways and our future goal is to apply our research to all applicable fields of human disease.